PiCSO clinical studies have demonstrated statistically significant improvements in:
- Infarct size reduction as a percent of left ventricular mass
- Index of microcirculatory resistance (IMR) 24h post procedure
How could PiCSO interventional trans-coronary sinus technology reduce heart failure post-STEMI? Watch video
Miracor Latest experience with PiCSO in STEMI patients Watch video
Miracor PiCSO therapy to reduce infarct size & clear microcirculation in STEMI patients Watch video
Scarsini R, Terentes-Printzios D, Shanmuganathan M, Kotronias RA, Borlotti A, Marin F, Langrish J, Lucking A, Ribichini F; Oxford Acute Myocardial Infarction (OxAMI) Study, Kharbanda R, Ferreira VM, Channon KM, De Maria GL, Banning AP. Pressure-controlled intermittent coronary sinus occlusion improves the vasodilatory microvascular capacity and reduces myocardial injury in patients with STEMI. Catheter Cardiovasc Interv. 2021 May 29.
De Maria GL, Alkhalil M, Borlotti A, et al. Index of microcirculatory resistance-guided therapy with pressure-controlled intermittent coronary sinus occlusion improves coronary microvascular function and reduces infarct size in patients with ST-elevation myocardial infarction: the Oxford Acute Myocardial Infarction – Pressure-controlled Intermittent Coronary Sinus Occlusion study (OxAMI-PiCSO study). EuroIntervention. 2018;14(3):e352-e359. Published 2018 Jun 8.
Mohl, W., D. Milasinovic, and D.P. Faxon. Amending a dogma. EuroIntervention, 2018. 14(12): p. e1258-e1261.
de Waha S, Patel MR, Granger CB, et al. Relationship between microvascular obstruction and adverse events following primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: an individual patient data pooled analysis from seven randomized trials. Eur Heart J. 2017;38(47):3502-3510.